[1P-084] Application of chromosome engineering technology (12): Analysis of antibody affinity maturation in fully human antibody producing mice

^○Takashi Moriwaki^1,2, Hiroyuki Satofuka², Satoshi Abe³, Hiroshi Tanaka³, Kayoko Morimoto³, Kazuma Tomizuka⁴, Mitsuo Oshimura³, Yoshihiro Baba⁵, Yasuhiro Kazuki^1,2,6 (1.Div. of Chr. Biomed. Eng., Grad. Sch. of Med. Sci., Tottori Univ., 2.CERC, Tottori Univ., 3.Trans Chromosomics Inc., 4.Lab. of Bioeng., Sch. of Life Sci., Tokyo Univ. of Pharm. and Life Sci., 5.Div. Immunol. and Genome Biol., Depart. of Mol. Genet., Med. Inst. of Bioreg., Kyushu Univ., 6.Chr. Eng. Group, ExCELLS)