Hypomyelinating leukodystrophy 8 (HLD8)-associated mutation of POLR3B leads to defective oligodendroglial morphological differentiation whose effect is reversed by ibuprofen.

Sui Sawaguchi

[1P-711] Hypomyelinating leukodystrophy 8 (HLD8)-associated mutation of POLR3B leads to defective oligodendroglial morphological differentiation whose effect is reversed by ibuprofen.

^○Sui Sawaguchi¹, Remina Shirai², Junji Yamauchi² (1.Lab. of Molecular Neurol., Dept. of Life Sci., Grad. Sch. of Life Sci., Tokyo Univ. of Pharmacy and Life Sci., 2.Lab. of Molecular Neurol., Tokyo Univ. of Pharmacy and Life Sci.)

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The 45th Annual Meeting of the Molecular Biology Society of Japan

[1P-711] Hypomyelinating leukodystrophy 8 (HLD8)-associated mutation of POLR3B leads to defective oligodendroglial morphological differentiation whose effect is reversed by ibuprofen.

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