[2P-078] The gene expression and epigenetic regulation of individual nuclei within the same multinucleated osteoclast is heterogeneous: Evidence from Intra-single cell sequencing (iscSeq)

^○Okada Hiroyuki^1,2, Terui Yuta³, Omata Yasunori^2,4, Tani Shoichiro^1,2, Terashima Asuka⁴, Saito Taku², Baron Roland^2,5, Tanaka Sakae², Chung Ungil^1,6, Hojo Hironori^1,6 (1.Cent. of Disease Biol., Grad. Sch. of Med., Univ. of Tokyo, 2.Dept. of Orthop. Surg., Grad. Sch. of Med., Univ. of Tokyo, 3.Biotech. Sect. 1, Product Strategy Dept., Marketing Cent., Life Business HQ, Yokogawa Electric Corp., 4.Bone and Cartilage Rege. Med., Univ. of Tokyo Hosp., 5.Dept. of Oral Med., Infection, and Immunity, Harvard Sch. of Dental Med., 6.Dept. of Bioengi., Grad. Sch. of Engine., Univ. of Tokyo)