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[2PW-03-4] Endothelin A receptor mutations cause rare human diseases by enhancing ligand binding capacity through allosteric effects

Yukiko Kurihara1, Toru Ekimoto2, Gordon Christopher3, Akiyasu Iwase1, Yasunobu Uchijima1, Ryo Sugiyama1, Mitsunori Ikeguchi2, Jeanne Amiel3, Hiroki Kurihara1 (1.Dept. of Physiol. Chem. Metab., Grad. Sch. of Med., Univ. of Tokyo, 2.Dept. of Med. Life Sci., Grad. Sch. of Med. Life Sci., Yokohama City Univ., 3.INSERUM, Necker Hosp.)

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