[3P-062] IN VITRO RECONSTITUTION REVEALS COOPERATIVE MECHANISMS OF ADAPTER PROTEIN-MEDIATED ACTIVATION OF PHOSPHOLIPASE C-GAMMA1

^○Junya Wada¹, Udumbara Rathnayake¹, Lisa Jenkins², Avinash Singh³, Moose Mohammadi³, Ettore Appella², Paul Randazzo¹, Lawrence Samelson¹ (1.LCMB, CCR, NCI, NIH, 2.LCB, CCR, NCI, NIH, 3.Dept. of Biochem. and Mol. Pharm., Sch. of Med., NYU Langone Health)