[1P-223] Tissue-specific tRNA epitranscriptome adaptations fine-tune mRNA translation via influencing codon bias and optimality.

^○Daisuke Ando^1,2, Sherif Rashad^1,5, Thomas J Begley³, Peter C Dedon⁴, Kuniyasu Niizuma^1,5 (1.Dept. of Neurosurgical Eng. and Translational Neurosci., Tohoku Univ. Grad. Sch. of Med., 2.Dept. of Neurol., Tohoku Univ. Grad. Sch. of Med., 3.Dept. of Biol. Sci., Univ. at Albany, 4.Dept. of Biol. Eng., MIT, 5.Dept. of Neurosurg. Eng. and Translational Neurosci., Grad. Sch. of Biomed. Eng., Tohoku Univ.)