[2P-274_2SP-03-16] Physiological effects by charge-dependent structural dynamics of fuzzy coat region in Alzheimer’s disease-fold Tau filaments

^○Shingo Tamai^1,2, Takashi Nomura², Ryohei Kojima⁴, Atsushi Yamagata³, John Burke², Mikako Shirouzu³, Takeshi Fukuma⁵, Motomasa Tanaka^2,1 (1.Grad. Sch. of Med. & Dent. Sci., TMDU, 2.Lab. for Protein Conformation Diseases, RIKEN CBS, 3.Lab. for Protein Functional and Structural Biology, RIKEN BDR, 4.Grad. Sch. NanoLS., Kanazawa Univ., 5.WPI-NanoLSI, Kanazawa Univ.)