13:57 〜 14:00

[2SP-02-05_2P-186] The promising chemical modifications in the siRNA seed region that can avoid off-target effects by steric hindrance or thermodynamic stability

^○Seongjin An¹, Yoshiaki Kobayashi², Kohei Nomura³, Yasuaki Kimura³, Hiroshi Abe³, Akase Dai⁴, Misako Aida⁵, Kumiko UiTei^1,2 (1.Grad. Sch. of Frontier Sci., Univ. of Tokyo, 2.Grad. Sch. of Sci., Univ. of Tokyo, 3.Grad. Sch. of Sci., Nagoya Univ, 4.AIDI Center, Hiroshima Univ, 5.ORACC, Hiroshima Univ.)