[3P-361_2SP-05-02] Application of chromosome engineering technology (11): Development of a top-down approach to generate mice that retain minimalized HLA gene region derived from native human chromosome

^○Nanami Kishima¹, Hitomaru Miyamoto¹, Satoshi Abe², Kyotaro Yamazaki³, Akane Okada⁴, Wakana Nakagawa¹, Reika Yuno¹, Takashi Moriwaki^2,4, Narumi Uno⁵, Kazuma Tomizuka⁵, Yasuhiro Kazuki^1,2,3,4 (1.Div. of Chr. Biomed. Eng., Grad. Sch. of Med. Sci., Tottori Univ.,, 2.Sch. of Life Sci., Facul. of Med., Tottori Univ.,, 3.Chr. Eng. Group, ExCELLS：ExCELLS.,, 4.CERC, Tottori Univ., 5.Lab. of Bioeng., Sch. of Life Sci., Tokyo Univ. of Pharm. and Life Sci.)