[3P-489] Investigating the roles of PIEZO 1 and YAP in promoting osteogenesis and angiogenesis in 3D-printed vascularized bone organoids through mechanical stimulations

^○YUCHIH LO^1,2, YiTing Lai², YuCheng Kang³, YuMin Tsai³, TzuHui Chu², JiaFew Shyu^1,2 (1.Graduate Institute of Life Sciences, National Defense Medical Center, Taipei, Taiwan, ROC, 2.Dept. of Biology and Anatomy, National Defense Medical Center, Taipei, Taiwan, ROC, 3.School of medicine, National Defense Medical Center, Taipei, Taiwan, ROC)