[G202-3vn] 17. Biofunctional Chemistry, Biotechnology

[G202-3vn-06] Experimental and theoretical study on converting myoglobin into a stable domain-swapped dimer by utilizing a tight hydrogen bond network at the hinge region

^○Cheng Xie¹, Hiromitsu Shimoyama², Masaru Yamanaka¹, Satoshi Nagao¹, Hirofumi Komori⁴, Naoki Shibata³, Yoshiki Higuchi³, Yasuteru Shigeta², Shun Hirota¹ (1. Nara Inst. Sci. Tech. (NAIST), 2. Univ. of Tsukuba, 3. Univ. of Hyogo, 4. Kagawa Univ.)

[Lang.] English

Keywords:Domain swapping, Protein structure, Hydrogen bond network, Protein design, Molecular dynamics simulation