[1P] F. Disorders of the Nervous System 2

[1P-149] Downregulation of miR-140-5p attenuates memory impairment induced by amyloid-ß oligomer in an animal model possibly through Pin1 regulation

*Pariya Khodabakhsh¹, Maryam Bazrgar², Fatemeh Mohagheghi³, Siavash Parvardeh¹, Abolhassan Ahmadiani² (1. Department of Pharmacology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran, 2. Neuroscience Research Center, Shahid Beheshti University of Medical Science, Tehran, Iran, 3. Institute of Experimental Hematology, Center for Translational Cancer Research (TranslaTUM), School of Medicine, Technical University of Munich, Munich, Germany)

Keywords:Alzheimer's disease, Pin1, mir-140-5p, Amyloid-ß oligomer