Oral

[O1-3] Retro 3

Tue. Oct 29, 2019 3:00 PM - 4:00 PM Room 3 (Zuiun)

Chair：
Hiroshi Ishii (AIDS Research Center, National Institute of Infectious Diseases)
Tetsuro Matano (AIDS Research Center, National Institute of Infectious Diseases)

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3:00 PM - 3:15 PM

[O1-3-09] Nef-specific cytolytic CD4⁺ T-cell responses in a viremic SIV controller receiving acute-phase neutralizing antibody passive infusion

*Trang Thi Thu Hau^1,2, Takushi Nomura¹, Tetsuro Matano^1,2,3, Hiroyuki Yamamoto¹ (1. AIDS Research Center, National Institute of Infectious Diseases, Japan, 2. Graduate School of Medical Sciences and Center for AIDS Research, Kumamoto University , 3. Institute of Medical Science, University of Tokyo, Japan)

3:15 PM - 3:30 PM

[O1-3-10] Arrangement of the V_H and V_L domains in chimeric antigen receptor (CAR) affects the effector functions of HIV-targeted CAR-T cells

*Jun-ichi Nunoya¹, Eijiro Teramura¹, Michiaki Masuda¹ (1. Dokkyo Medical University, Department of Microbiology)

3:30 PM - 3:45 PM

[O1-3-11] Existence of replication-competent minor variants with different coreceptor usage suggests possible mechanism of the coreceptor switch in HIV-1 infection

*Yosuke Maeda¹, Taichiro Takemura², Chikata Takayuki^3,4, Takeo Kuwata^3,4, Hiromi Terasawa¹, Riito Fujimoto¹, Giang Van Trang³, Tomohiro Akahoshi³, Hayato Murakoshi^3,4, Kazuaki Monde¹, Tomohiro Sawa¹, Shuzo Matsushita¹, Trang Vu Nguyen³, Kinh Van Nguen⁵, Futoshi Hasebe², Tetsu Yamashiro², Masafumi Takiguchi^3,4 (1. Department of Microbiology, Faculty of Life Sciences, Kumamoto University, 2. Institute of Tropical Medicine, Nagasaki University, 3. Center for AIDS Research, Kumamoto University, 4. Joint Research Center for Human Retrovirus Infection, Kumamoto University, 5. National Hospital of Tropical Diseases, Dong Da District, Hanoi, Viet Nam)

3:45 PM - 4:00 PM

[O1-3-12] **Impact of T-cell escape mutations associated with a detrimental allele HLA-C*15:05 on clinical outcome of HIV-1 clade A/E-infected individuals**

*Hayato Murakoshi^1,2, Takayuki Chikata^1,2, Tomohiro Akahoshi², Masafumi Takiguchi^1,2 (1. Joint Research Center for Human Retrovirus Infection, Kumamoto University, 2. Center for AIDS Research, Kumamoto University)

Session information

[O1-3] Retro 3

[O1-3-09] Nef-specific cytolytic CD4⁺ T-cell responses in a viremic SIV controller receiving acute-phase neutralizing antibody passive infusion

[O1-3-10] Arrangement of the V_H and V_L domains in chimeric antigen receptor (CAR) affects the effector functions of HIV-targeted CAR-T cells

[O1-3-11] Existence of replication-competent minor variants with different coreceptor usage suggests possible mechanism of the coreceptor switch in HIV-1 infection

[O1-3-12] **Impact of T-cell escape mutations associated with a detrimental allele HLA-C*15:05 on clinical outcome of HIV-1 clade A/E-infected individuals**

Authentication

Session information

[O1-3] Retro 3

[O1-3-09] Nef-specific cytolytic CD4+ T-cell responses in a viremic SIV controller receiving acute-phase neutralizing antibody passive infusion

[O1-3-10] Arrangement of the VH and VL domains in chimeric antigen receptor (CAR) affects the effector functions of HIV-targeted CAR-T cells

[O1-3-11] Existence of replication-competent minor variants with different coreceptor usage suggests possible mechanism of the coreceptor switch in HIV-1 infection

[O1-3-12] Impact of T-cell escape mutations associated with a detrimental allele HLA-C*15:05 on clinical outcome of HIV-1 clade A/E-infected individuals

Authentication

[O1-3-09] Nef-specific cytolytic CD4⁺ T-cell responses in a viremic SIV controller receiving acute-phase neutralizing antibody passive infusion

[O1-3-10] Arrangement of the V_H and V_L domains in chimeric antigen receptor (CAR) affects the effector functions of HIV-targeted CAR-T cells

[O1-3-12] **Impact of T-cell escape mutations associated with a detrimental allele HLA-C*15:05 on clinical outcome of HIV-1 clade A/E-infected individuals**