[1P] F. Disorders of the Nervous System 2

[1P-216] Pathophysiological study of amyotrophic lateral sclerosis using gene edit human iPS cells

*Asako Onda-Ohto^1,2, Minami Hasegawa-Ogawa¹, Hiromasa Matsuno^1,2, Keiko Bono^1,2, Hiromi Hiraki^1,2, Yumi Kanegae³, Yasuyuki Iguchi², Hirotaka James Okano¹ (1. 1.Division of Regenerative Medicine, Research Center for Medical Sciences, The Jikei University School of Medicine, Tokyo, Japan, 2. 2.Division of Neurology, The Jikei University School of Medicine, Tokyo, Japan, 3. 3.Core Research Facilities, Research Center for Medical Sciences, The Jikei University School of Medicine, Tokyo, Japan)

Keywords:amyotrophic lateral sclerosis, induced pluripotent stem cells, CRISPR/Cas9, oxidative stress