[2P] C. Sensory and Motor Systems 1

[2P-265] Pharmacological improvement of histone modulation in the spinal cord suppresses persistent allodynia under the postsurgical pain-state

*Kenichi Tanaka^1,2, Yosuke Katsuda^1,3, Michiko Narita^2,4, Hideyuki Takeshima⁵, Yusuke Hamada^1,2, Daisuke Sato^1,2, Masako Iseki³, Naoko Kuzumaki^1,2, Toshikazu Ushijima⁵, Minoru Narita^1,2,3 (1. Dept. Pharmacol., Hoshi Univ., Tokyo, Japan, 2. Div. Pathophysiol., Natl. Cancer Ctr. Res. Inst., Tokyo, Japan, 3. Dept. Anesthesiol., Pain Med., Juntendo Univ., Tokyo, Japan, 4. Dept. Mol and Cell Med., Tokyo Medical., Univ., Tokyo, Japan, 5. Div. Epigenomics, Natl. Cancer Ctr. Res. Inst., Tokyo, Japan)

Keywords:Chronic postsurgical pain, spinal cord, synaptic plasticity, epigenetics