[20p-C301-1~17] 3.3 Biomedical optics (formerly 3.4)

△ [20p-C301-17] Proposal and demonstration of light-sheet Brillouin scattering microscopy

〇(PC)Ayumu Ishijima^1,2, Shinga Okabe¹, Ichiro Sakuma¹, Keiichi Nakagawa¹ (1.Univ. Tokyo, 2.PRESTO JST)

Keywords:Brillouin light scattering, Picosecond ultrasonics, Cell imaging

We report light-sheet Brillouin scattering microscopy that enables single-shot two-dimensional imaging of cellular elasticity. We realized it by extending our dispersive coherent Brillouin scattering spectroscopy, which achieves high-speed Brillouin oscillation measurement by multi-channel detection of time-domain Brillouin oscillations in the frequency domain, into the two-dimensional measurement. Here, we present experimental results showing the possibility of achieving three-orders faster image acquisition than the previous world's fastest Brillouin scattering microscopy.