The activated microglia and impaired glutamatergic neurotransmission via upregulating the TNF-a/TNFR1 signaling pathway in the mice exposed to repeated social defeat stress as juveniles

Mikio Yoshida

[P491] The activated microglia and impaired glutamatergic neurotransmission via upregulating the TNF-a/TNFR1 signaling pathway in the mice exposed to repeated social defeat stress as juveniles

*Mikio Yoshida¹, Hikari Katada¹, Yuya Isozumi¹, Shunya Kawai¹, Itaru Kushima², Akira Yoshimi¹, Norio Ozaki³, Yukihiro Noda¹ (1. Division of Clinical Sciences and Neuropsychopharmacology, Meijo University, Faculty and Graduate School of Pharmacy, 2. Department of Psychiatry, Nagoya University, Graduate School of Medicine, 3. Pathophysiology of Mental Disorders, Nagoya University, Graduate School of Medicine)

Keywords:Social defeat stress exposure as juveniles, Microglia, Glutamatergic neurotransmission

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Childhood & Adolescent Disorders

[P491] The activated microglia and impaired glutamatergic neurotransmission via upregulating the TNF-a/TNFR1 signaling pathway in the mice exposed to repeated social defeat stress as juveniles

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