[CThA15E] Raman Imaging

[CThA15E-04] Raman Imaging of Primary Cultured Hippocampal Neuron for Evaluating Neuronal Maturation

*Takahiro Nagano^1,2, Kyoko Masui^1,3,4, Yasunori Nawa^1,2, Hidekazu Ishitobi^1,2,4, Tomomi Tani⁵, Satoshi Fujita^1,2, Katsumasa Fujita^1,2, Chie Hosokawa^1,3, Yasushi Inouye^1,2,4 (1. PhotoBIO-OIL, AIST (Japan), 2. Appl. Phys. Osaka Univ. (Japan), 3. Osaka City Univ. (Japan), 4. Front. Biosci., Osaka Univ. (Japan), 5. Biomed. Res. Inst., AIST (Japan))

[Presentation Style] Onsite

We investigated the distribution changes of cytochrome c in mitochondria of neurons by Raman imaging. Cytochrome c gradually spread to neurites, implying that mitochondria increased in areas of high energy demand, including synaptic site.