R2: Crystal structure, crystal chemistry, physical properties of minerals, crystal growth and applied mineralogy

[R2-05] Effect of the Ionic Radius of Monovalent Ions on Octacalcium Phosphate Formation

*Yuki Sugiura Sugiura¹, Yasuko Saito², Takashi Endo², Yoji Makita¹ (1. AIST HRI, 2. AIST RISC)

Keywords:Calcium phosphate, bone substitute, biomaterial, Biomineralization

Octacalcium phosphate (OCP), a layered calcium phosphate compound, is an attractive material for new medical combination products, which are hybrid materials consisted of both drugs and biomaterials that have shown excellent therapy scores. OCP is fabricated primarily from soluble calcium salt via an aqueous-mediated hydrolysis process. The co-existing cations are likely to be incorporated into the OCP unit lattice during this process and affect the development of the OCP crystal structure and its thermodynamic stability.