*Kengo Miyo^1,5,8, Hiroshi Okamura², Yoshihiro Aoyagi³, Kazuhiro Suzuki⁴, Hiroyuki Hoshimoto⁵, Keiko Ota^2,7, Masamichi Ishii⁵, Mika Ogasawara⁶ (1. Japan Health Research Promotion Bureau, 2. Osaka Metropolitan University Hospital , 3. National Cancer Center Hospital East, 4. Cancer Institute Hospital of JFCR, 5. National Center for Global Health and Medicine , 6. Pfizer R&D Japan G.K., 7. Ehime University Graduate School of Medicine, 8. Graduate School of Medicine, the University of Tokyo)

*Kengo Miyo^1,2 (1. Japan Health Research Promotion Bureau, 2. Graduate School of Medicine, the University of Tokyo)

*Kazuhiro Suzuki¹ (1. Cancer Institute Hospital of JFCR)

*Hiroyuki Hoshimoto¹, Kengo Miyo¹ (1. National Center for Global Health and Medicine)

*Keiko Ota^1,2 (1. Osaka Metropolitan University, 2. Ehime University)

*Masamichi Ishii¹ (1. National Center for Global Health and Medicine)

*Yoshihiro Aoyagi¹ (1. National Cancer Center Hospital East)

*Mika Ogasawara¹ (1. Pfizer R&D Japan)

*Hideto Yokoi Yokoi¹, Takashi Morita², Yusuke Odani¹ (1. Department of Medical Informatics, Kagawa University Hospital, 2. Osaka General Medical Center)

*Hideto Yokoi¹ (1. Department of Medical Informatics, Kagawa University Hospital)

*Takashi Morita¹ (1. Osaka General Medical Center)

*Yusuke Odani¹ (1. Kagawa University Hospital)

*Takanori Fujita^1,2, Takashi Okumura³, Seiji Bito⁴, Ken Ogata⁵, Shunsuke Mizobata⁶, Daisuke Sato⁷, Shigeto Yonemura⁵ (1. Keio University, 2. Kanagawa University of Human Services, 3. Kitami Institute of Technology, 4. National Hospital Organization Tokyo Medical Center, 5. University of Tokyo, 6. TMI Associates, 7. Fujita Health University)

*Shigeto Yonemura Yonemura¹ (1. The University of Tokyo)

*Takashi Okumura¹ (1. Kitami Institute of Technology)

*Seiji Bito¹ (1. Division of Clinical Epidemiology, NHO Tokyo Medical Center)

*Shunsuke Mizobata¹ (1. TMI Associates)