Analyzing the Stability of Autocatalytic Chemical Reaction Networks Based on their Amplification Rate

Hideshi Ooka; Sahaya Vijay Jeyaraj; Ryuhei Nakamura

Presentation information

[J] Oral

U (Union ) » Union

[U-12] Biogeochemistry of CO world

Thu. May 29, 2025 10:45 AM - 12:15 PM Exhibition Hall Special Setting (1) (Exhibition Hall 7&8, Makuhari Messe)

convener:Yuichiro Ueno(Department of Earth and Planetary Sciences, Tokyo Institute of Technology), Norio Kitadai(Japan Agency for Marine-Earth Science and Technology), Shino Suzuki(RIKEN), Kazumi Ozaki(Tokyo Institute of Technology), Chairperson:Norio Kitadai(Japan Agency for Marine-Earth Science and Technology), Shino Suzuki(RIKEN)

11:45 AM - 12:00 PM

[U12-10] Analyzing the Stability of Autocatalytic Chemical Reaction Networks Based on their Amplification Rate

*Hideshi Ooka¹, Sahaya Vijay Jeyaraj¹, Ryuhei Nakamura^1,2 (1.RIKEN, 2.Science Tokyo)

Keywords:Autocatalysis, Diffusion, Chemical Reaction Network, Protometabolism

Chemical species diffuse away in open systems such as the natural environment. In such an environment, mechanisms to increase the amount of chemical species such as autocatalysis are necessary to maintain their concentrations. In this study, we have evaluated the stability of autocatalytic networks and show that a higher autocatalytic amplification is necessary for larger networks with more chemical species. This result suggests that the development of new enzymes with higher activity was necessary to expand the size of protometabolic networks.