*Akiho Sunami1, Masanao Inokoshi1, Muneaki Tamura2, Rena Takahashi3, Keita Hatano1, Shunsuke Minakuchi1
(1. Department of Gerodontology and Oral Rehabilitation, Division of Gerontology and Gerodontology, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, 2. Department of Microbiology and Immunology, Nihon University School of Dentistry, Japan, 3. Department of Cariology and Operative Dentistry, Graduate School of Medical and Dental Sciences, Tokyo Medical and Dental University, Japan)