[EP-14] Relationship between occlusal force and peri-implant bone metabolism
[Abstract]
[Objective]
Peri-implantitis and peri-implant bone resorption are common issues that can impact the effectiveness of implant treatments over time, while mechanical stress plays a significant role in the regulation of bone formation and resorption1). However, it is unclear how peri-implant bone responds to occlusal loading and the change in occlusal balance. This study investigated the relationship between occlusal force and peri-implant bone remodeling.
[Method]
Experiment 1: The maxillary right first molar was extracted from 5-week-old Wistar rats (15 males; weight 120–130 g). One week later, implants with crown heights of 0.5 mm (0.5 group), 1.0 mm (1.0 group), or 1.5 mm (1.5 group) were implanted at the extraction site.
Experiment 2: The maxillary right first molar was extracted from 5-week-old Wistar rats (15 males; weight 120–130 g), and a 1.0 mm crown was implanted. Four weeks after implantation, the maxillary right second and third molars were extracted from the ipsilateral tooth loss loading (ILL) group, while the maxillary left first and second molars were extracted from the contralateral tooth loss loading (CLL) group. No tooth was extracted in the control group.
Five weeks after implant surgery, the rats were euthanized. Samples were isolated to prepare the ground sections and the frozen sections for morphological and histological observation.
[Results and Discussion]
Data were analysed using Bonferroni post-hoc analysis and one-way analysis of variance (ANOVA).
In Experiment 1, the bone-implant contact rate (BIC%) was significantly higher in the 1.0 and 0.5 groups than the 1.5 group, and the bone area rate (BA%) was significantly higher in the 1.5 group than the 0.5 group. In Experiment 2, the control group had a significantly higher BIC% than the ILL and CLL groups; however, there was no intergroup difference in the BA%.
During the initial healing phase, high mechanical stimulation prevented the establishment of osseointegration but promoted peri-implant bone formation. After long-term treatment, the increased occlusal load disrupted the established osseointegration, which may lead to peri-implant bone resorption.
[References]
1) Solderer A, Al-Jazrawi A, Sahrmann P et al. Removal of failed dental implants revisited: Questions and answers. Clin Exp Dent Res. 2019 (21)8:712-724.
[Objective]
Peri-implantitis and peri-implant bone resorption are common issues that can impact the effectiveness of implant treatments over time, while mechanical stress plays a significant role in the regulation of bone formation and resorption1). However, it is unclear how peri-implant bone responds to occlusal loading and the change in occlusal balance. This study investigated the relationship between occlusal force and peri-implant bone remodeling.
[Method]
Experiment 1: The maxillary right first molar was extracted from 5-week-old Wistar rats (15 males; weight 120–130 g). One week later, implants with crown heights of 0.5 mm (0.5 group), 1.0 mm (1.0 group), or 1.5 mm (1.5 group) were implanted at the extraction site.
Experiment 2: The maxillary right first molar was extracted from 5-week-old Wistar rats (15 males; weight 120–130 g), and a 1.0 mm crown was implanted. Four weeks after implantation, the maxillary right second and third molars were extracted from the ipsilateral tooth loss loading (ILL) group, while the maxillary left first and second molars were extracted from the contralateral tooth loss loading (CLL) group. No tooth was extracted in the control group.
Five weeks after implant surgery, the rats were euthanized. Samples were isolated to prepare the ground sections and the frozen sections for morphological and histological observation.
[Results and Discussion]
Data were analysed using Bonferroni post-hoc analysis and one-way analysis of variance (ANOVA).
In Experiment 1, the bone-implant contact rate (BIC%) was significantly higher in the 1.0 and 0.5 groups than the 1.5 group, and the bone area rate (BA%) was significantly higher in the 1.5 group than the 0.5 group. In Experiment 2, the control group had a significantly higher BIC% than the ILL and CLL groups; however, there was no intergroup difference in the BA%.
During the initial healing phase, high mechanical stimulation prevented the establishment of osseointegration but promoted peri-implant bone formation. After long-term treatment, the increased occlusal load disrupted the established osseointegration, which may lead to peri-implant bone resorption.
[References]
1) Solderer A, Al-Jazrawi A, Sahrmann P et al. Removal of failed dental implants revisited: Questions and answers. Clin Exp Dent Res. 2019 (21)8:712-724.