[15a-B8-1~12] 12.7 Biomedical Engineering and Biochips

△ [15a-B8-8] Development of a Fast Detection Method of Endotoxin

〇Masato Yasuura¹, Koji Ueno², Makoto Fujimaki¹ (1.AIST, 2.C&I)

Keywords:optical-sensing, endotoxin, gelation

It is necessary for medicines and disposable equipments to provide endotoxin-free products in the medical and pharmaceutical industries. However, the endotoxin test using limulus amebocyte lysate (LAL) takes over 30 minutes at 37 degrees centigrade. In this study, we developed a fast detection method of endotoxin using a waveguide-mode structure. Using this method, we detected 0.1EU/ml endotoxin in 10 minutes incubation at room temperature.