[21a-W621-1~12] 8.6 Plasma life sciences

△ [21a-W621-7] Scavenging effect of reactive oxygen and nitrogen species in the plasma-activated-medium

〇(M2)Naoyuki Kurake¹, Hiromasa Tanaka¹, Kenji Ishikawa¹, Hiroshi Hashizume¹, Kae Nakamura², Hiroaki Kajiyama², Fumitaka Kikkawa², Takashi Kondo³, Masaaki Mizuno², Keigo Takeda¹, Hiroki Kondo¹, Makoto Sekine¹, Masaru Hori¹ (1.Nagoya Univ. Eng., 2.Nagoya Univ. Med., 3.Toyama Univ.)

Keywords:non equilibrium atmospheric plasma,cancer,scavenger

Plasma-activated-medium (PAM) can selectively kill a cancer cells without killing normal cells. However, this antitumor mechanism was still unclear. In the last time, we reported about generations by the plasma irradiation and antitumor contribution of hydrogen peroxide and nitrite with focusing on the reactive oxygen and nitrogen species (RONS). In this study, we investigated a new antitumor mechanism appeared by using scavengers for separating effects of RONS.