[16a-P3-1~32] 12.7 Biomedical Engineering and Biochips

▲ [16a-P3-24] High Sensitive Detection of Prostate Specific Antigen Using Photonic Crystal Nanocavity Resonator

〇(DC)Amrita Kumar Sana¹, Yoshiteru Amemiya¹, Takeshi Ikeda¹, Akio Kuroda¹, Shin Yokoyama¹ (1.Hiroshima Univ.)

Keywords:prostate specific antigen, biosensor, photonic crystal

To detecting a very small of biomarker in human blood are very important for early diagnosis of severe diseases. We succeeded in sensing the antibody–antigen reaction using photonic crystal double nanocavity resonator sensor employing PSA marker as an example target. By optimizing the immobilization of the target biomarker, we detected the PSA concentration as low as 0.01 ng/mL. Thus, our PhC based double nanocavity resonator may be promising candidate as practical biomolecules sensor in the medical diagnosis.