[18a-221C-1~10] 12.7 Biomedical Engineering and Biochips

△ [18a-221C-6] Efficient stimulation of hiPSC-derived cardiomyocytes by hydrogel culture dish with molecular, electrical and optical transparency

〇Kensuke Sumomozawa¹, Shotaro Yoshida¹, Matsuhiko Nishizawa¹ (1.Tohoku Univ.)

Keywords:hydrogel

Studies to apply cardiomyocytes derived from human iPS cells to treatment of cardiac diseases and drug testing are active, but immature cardiomyocytes cause arrhythmia and the like, so it is necessary to promote cell maturation by pulsed electrical stimulation Has been done. In this study, by integrating an organic electrode PEDOT / PU with a high electric capacity into a hydrogel having a molecule, electricity, and optically permeable, which has a chamber for fixing cells, efficient use of hiPSC-derived cardiomyocytes We developed a culture dish that can be stimulated electrically.