[20a-221C-1~10] 12.7 Biomedical Engineering and Biochips

▼ [20a-221C-6] Micro LED-based photo-stimulation devices integrated with microdialysis functionality for optogenetics

〇(M1)Mark Guinto¹, Yasumi Ohta¹, Mamiko Kawahara¹, Kyosuke Naganuma¹, Makito Haruta¹, Toshihiko Noda¹, Kiyotaka Sasagawa¹, Takashi Tokuda¹, Jun Ohta¹ (1.NAIST)

Keywords:optogenetics, micro LED, microdialysis

Optogenetics is a recently developed technique that uses light to perturb the neural excitation process, allowing for a more direct investigation of neural activity and its correspondence to animal behavior. In this regard, advancements in both the functionality and structural conformability of optogenetic devices will be invaluable to neuro-scientific research. Herein, we demonstrate multiple lightweight implantable devices capable of optical stimulation and concurrent monitoring of neurotransmitter levels near the cortical surface and in deep brain regions by strategically integrating micro-LEDs with microdialysis probes.