[18p-P5-1~22] 12.6 Nanobiotechnology

[18p-P5-10] Investigation for Properties of Artificial Lipid Bilayer on Surface Modified Substrate and Application to Membrane Protein Reconstruction System

〇Hiroyuki Hoshino¹, Kota Sakamoto², Fumio Hayashi², Minoru Hanaya¹, Masashi Sonoyama¹, Toshinori Motegi¹ (1.Gunma Univ., 2.Center for Instrumental Analysis, Gunma Univ.)

Keywords:Supported lipid bilayer, membrane protein

Supported lipid bilayer (SLB) has the possibility of being useful for understanding the membrane protein structure etc. from the planarity, however, it does not protect peripheral portions of transmembrane proteins from random orientation and denaturation if they come in contact with the substrate. In this study, we aim to form self-assembled monolayer (SAM) bound to specific site of membrane protein on mica, And SLB was formed on there.