[10p-Z03-1~7] Frontier of Research on Mechanism of Plasma-induced Biological Reactions

[10p-Z03-6] Spontaneous and genome-integration free external molecular/gene introduction by complex stimulus generated with discharge plasm introduction and its applications

〇Masafumi Jinno^1,3, Yoshihisa Ikeda¹, Hideki Motomura¹, Yugo Kido², Susumu Satoh^3,1 (1.Ehime Univ., 2.Pearl Kogyo Co. Ltd., 3.i-Gene Co. Ltd.)

Keywords:gene introduction, molecular introduction, genome editing

In 2002 the plasma gene/molecular introduction into cells was discovered, and we have been working on revealing the mechanism of this phenomenon. Then we have found that this method is Gene-integration free that is a unique characteristic useful for medical, agricultural and other practical applications, while the others usually cause genome-integrations. Here, we will introduce the plasma molecule/gene transfer method and its known mechanism, and the development of its applications from cultured animal cells to the fields of medicine and agriculture and fisheries.