[15a-B309-1~5] 3.4 Biomedical optics

[15a-B309-5] Cancer Detection Using Scattering of Circularly-Polarized Light

〇Nozomi Nishizawa¹, Bassam Al-Qadi², Takahiro Kuchimaru³, Hiro Munekata¹ (1.FIRST, TITECH, 2.Palestine Tech. Univ., 3.Jichi Med. Univ.)

Keywords:Biosensing, Circularly polarized light, Cancer diagnosis

The polarization of light multiply scattered by biological tissues against incident circular polarization has been considered as a powerful tool for the diagnosis of tumor tissue, particularly pre-cancerous lesions. It is reported that the polarization state of scattered light against incident circular polarization can discriminate between ablated cancerous and non-cancerous tissue in vitro with the incident light with 639 nm of wavelength. Based on these reports, we proposed a non-staining, non-invasive and in-vivo cancer diagnosis technique using spin-LEDs and spin-PDs which can directly emit and detect circularly polarized light. Reported in this paper is the incident and detection angle dependence of polarization of light scattered by sliced biological tissues using circularly polarized light with 900 nm of wavelength which is the emission wavelength of spin-LED and has relatively small absorptance in bio-tissues.