[10p-S402-1~18] 12.7 Biomedical Engineering and Biochips

[10p-S402-11] Evaluation of skin penetration properties of polymeric microneedle shapes

〇Mizuki Inada¹, Yukihiro Kanda¹, Hiroaki Takehara^1,2, Takanori Ichiki^1,2 (1.U Tokyo, 2.iCONM)

Keywords:microneedles, polymer

Microneedles made of polymeric materials are attracting attention as a minimally invasive transdermal drug delivery technology in the medical field from the viewpoint of safety. In order to achieve minimally invasive penetration, the microneedles need to have a small root diameter and a small load required for penetration. In this study, we first investigated the optimal microneedle shape for skin implantation using elasto-plastic deformation analysis. After that, the actual molded microneedles were evaluated for skin penetration, and the validity of the analysis results was verified.