[11a-N201-1~10] Optical/magnetic control of biological functions for the elucidation of biological systems

[11a-N201-6] Development of techniques to create novel neural circuits with optogenetics

〇Yoshito Masamizu^1,2, Teppei Ebina³, Yasuhiro Tanaka⁴, Midori Negishi-Kato⁵, Hiroaki Onoe⁶, Shoji Takeuchi⁷, Masanori Matsuzaki^3,8 (1.Grad Sch Brain Sci, Doshisha Univ, 2.PRESTO, JST, 3.Grad Sch Med, Univ of Tokyo, 4.Grad Sch Brain Sci, Tamagawa Univ, 5.Fac Pharm, Musashino Univ, 6.Grad Sch Sci Tech, Keio Univ, 7.Grad Sch Info Sci Tech, Univ of Toky, 8.RIKEN CBS)

Keywords:Neuronal fiber, In vivo calcium imaging

A constructive approach would be useful to reveal the brain's information-processing mechanisms. At first, to create new neural circuits, we established a system to produce a neuronal fiber with a double-coaxial laminar flow microfluidic device. Next, to perform in vivo calcium imaging, we developed protocols to make rodents and non-human primates perform movement tasks with the head-fixed condition. In the future, we would like to elucidate the brain's information-processing mechanisms using these techniques.