4:30 PM - 4:45 PM
▼ [23p-E105-11] Nanoparticulate modified microelectrode for acetylcholine detection by fast-scan cyclic voltammetry
Keywords:Nanoparticle, Fast-scan cyclic Voltammetry, Acetylcholine
Acetylcholine (ACh) is an essential neurotransmitter that presents in both the peripheral and central nervous systems of the brain. Which has an important role in processing memory and learning. Therefore, the lack of it is associated with a brain disorder such as Alzheimer’s disease, Parkinson’s disease.
Fast-scan cyclic voltammetry (FSCV) is the real-time monitoring of neurotransmitters in the brain. Moreover, FSCV offers many advantages, including millisecond time resolution, moderate selectivity, and high sensitivity. Metal oxide nanoparticles modified electrodes have shown a good performance through increasing the surface area and enhancing the mass transport. Iron oxide (Fe2O3) and copper oxide (CuO) are exhibited good electrical conductivity which is ubiquitous in electrocatalytic behavior.
This study aimed to develop and modify the flexible microelectrode with metal oxide nanoparticles and multiwall carbon nanotubes (MWCNTs) as the electrochemical sensor for acetylcholine detection.
Fast-scan cyclic voltammetry (FSCV) is the real-time monitoring of neurotransmitters in the brain. Moreover, FSCV offers many advantages, including millisecond time resolution, moderate selectivity, and high sensitivity. Metal oxide nanoparticles modified electrodes have shown a good performance through increasing the surface area and enhancing the mass transport. Iron oxide (Fe2O3) and copper oxide (CuO) are exhibited good electrical conductivity which is ubiquitous in electrocatalytic behavior.
This study aimed to develop and modify the flexible microelectrode with metal oxide nanoparticles and multiwall carbon nanotubes (MWCNTs) as the electrochemical sensor for acetylcholine detection.