Oral Presentation12 Metabolism

[OP12e-3] The polyol pathway functions as an intracellular and systemic glucose sensor impacting metabolism and development

ポリオール経路は細胞内および全身性のグルコースセンサーとして機能することにより代謝および発生を制御する

*Hiroko Sano¹, Akira Nakamura², Mariko Yamane², Hitoshi Niwa², Takashi Nishimura³, Kimi Araki^4,5, Kazumasa Takemoto^2,4, Kei-ichiro Ishiguro², Hiroki Aoki⁶, Yuzuru Kato⁷, Ryo Hoshino⁸, Yuto Yoshinari^3,9, Ryusuke Niwa⁹, Masayasu Kojima¹ (1. Institute of Life Science, Kurume University, 2. Institute of Molecular Embryology and Genetics, Kumamoto University, 3. Institute for Molecular and Cellular Regulation, Gunma University, 4. Institute of Resource Development and Analysis, Kumamoto University, 5. Center for Metabolic Regulation of Healthy Aging, Kumamoto University, 6. Cardiovascular Research Institute, Kurume University, 7. Department of Gene Function and Phenomics, National Institute of Genetics, 8. Graduate School of Science and Technology, University of Tsukuba, 9. Life Science Center for Survival Dynamics, Tsukuba Advanced Research Alliance, University of Tsukuba)

Keywords:Glucose sensing, Mondo/ChREBP, Metabolism, Germline stem cell