4:10 PM - 5:10 PM
[YB02-01] 磁気共鳴feature tracking strainを用いたフォンタン術後患者の心機能評価
Keywords:Fontan palliation、cardiac magnetic resonance、feature tracking strain
Objective: To investigated into cine-based feature tracking strain (FTS) in single ventricle subjects after Fontan palliation undergoing cardiac magnetic resonance (CMR).
Methods: 18 Fontan subjects (mean age 17.6+/-9.2 years, post Fontan period 14.2+/-8.2 years, 13/18 morphologic right ventricle, 5/18 morphologic left ventricle) underwent a CMR study. Single ventricular end-diastolic and -systolic volumes (SVEDV and SVESV), stroke volume (SV), and ejection fraction (EF) were measured as conventional function parameters. Global longitudinal and circumferential strain/strain rate (GLS/GLSR and GCS/GCSR), and radial strain/SR are calculated using FTS. Anterior to posterior wall motion delay (＜130ms;APWMD) analysis was performed on the short-axis view at the basal level, and bilateral wall motion delay (＜90ms;BLWMD) on the 4-chamber view at the basal and mid levels.
Results: Basal GCS/GCSR were lower than it at the mid (p=0.02 and 0.02) and apical (p=0.001 and 0.003) levels. There were correlations between GLS/GLSR and GCS/GCSR, and SVEDV (r=0.51 to 0.73). At the mid and apical levels, there were correlations between GCS/GCSR and SVESV, and EF (r=0.66 to 0.85 and r=0.52 to 0.79). There was also correlation between GLSR and SV (r=0.73). BLWMD was found for 12 cases (67%) at the basal and 10 cases (56%) at mid levels, and APWMD for 4 cases (22%) at the basal level.
Conclusions: Basal ventricular dysfunction suggested by low GCS/GCSR and BLWMD. Analysis of regional strain/SR may helpful in understanding myocardial mechanics in the single ventricle in further studies.
Methods: 18 Fontan subjects (mean age 17.6+/-9.2 years, post Fontan period 14.2+/-8.2 years, 13/18 morphologic right ventricle, 5/18 morphologic left ventricle) underwent a CMR study. Single ventricular end-diastolic and -systolic volumes (SVEDV and SVESV), stroke volume (SV), and ejection fraction (EF) were measured as conventional function parameters. Global longitudinal and circumferential strain/strain rate (GLS/GLSR and GCS/GCSR), and radial strain/SR are calculated using FTS. Anterior to posterior wall motion delay (＜130ms;APWMD) analysis was performed on the short-axis view at the basal level, and bilateral wall motion delay (＜90ms;BLWMD) on the 4-chamber view at the basal and mid levels.
Results: Basal GCS/GCSR were lower than it at the mid (p=0.02 and 0.02) and apical (p=0.001 and 0.003) levels. There were correlations between GLS/GLSR and GCS/GCSR, and SVEDV (r=0.51 to 0.73). At the mid and apical levels, there were correlations between GCS/GCSR and SVESV, and EF (r=0.66 to 0.85 and r=0.52 to 0.79). There was also correlation between GLSR and SV (r=0.73). BLWMD was found for 12 cases (67%) at the basal and 10 cases (56%) at mid levels, and APWMD for 4 cases (22%) at the basal level.
Conclusions: Basal ventricular dysfunction suggested by low GCS/GCSR and BLWMD. Analysis of regional strain/SR may helpful in understanding myocardial mechanics in the single ventricle in further studies.