16:55 〜 17:45
[I-OR13-01] Feature tracking MRIを用いたストレイン解析による術後ファロー四徴症右室心筋deformationの評価
キーワード：tetralogy of Fallot, myocardial deformation, pulmonary regurgitation
Background: Pulmonary regurgitation influences long-term ventricular mechanism in repaired tetralogy of Fallot (TOF). The objective of this study was to investigate into relationships RV myocardial deformation with cardiac MRI (CMR) functional parameters.
Methods: 25 repaired TOF patients and 10 normal controls retrospectively underwent a CMR study. RV global longitudinal strain (GLS) was measured from the standard 2-chamber and 4-chamber view, and global circumferential strain (GCS) at the RV mid cavity from the standard short axis view. GLS and GCS were offline performed using Cine-based feature tracking strain.
Results: 92% of cases have obvious pulmonary regurgitation [regurgitant fraction (PRRF)=34±18%]. GLS was reduced in TOF compared to controls while GCS was preserved. GLS, GCS and longitudinal to circumferential strain (L/C) were correlated with right ventricular ejection fraction (RVEF), and negatively correlated RV volume. There was no correlation between GLS, GCS and L/C, and PRRF.
Conclusions: The correlations between GLS, GCS and L/C with RV volumes and RVEF without PRRF. RV myocardial deformation may provide insight into right ventricular response to volume overload in TOF.
Methods: 25 repaired TOF patients and 10 normal controls retrospectively underwent a CMR study. RV global longitudinal strain (GLS) was measured from the standard 2-chamber and 4-chamber view, and global circumferential strain (GCS) at the RV mid cavity from the standard short axis view. GLS and GCS were offline performed using Cine-based feature tracking strain.
Results: 92% of cases have obvious pulmonary regurgitation [regurgitant fraction (PRRF)=34±18%]. GLS was reduced in TOF compared to controls while GCS was preserved. GLS, GCS and longitudinal to circumferential strain (L/C) were correlated with right ventricular ejection fraction (RVEF), and negatively correlated RV volume. There was no correlation between GLS, GCS and L/C, and PRRF.
Conclusions: The correlations between GLS, GCS and L/C with RV volumes and RVEF without PRRF. RV myocardial deformation may provide insight into right ventricular response to volume overload in TOF.