4:55 PM - 5:45 PM
[I-OR13-04] Feature tracking磁気共鳴ストレインによるFontan循環における右室型及び左心型単心室の心筋機能の比較
Keywords:Fontan, myocardial dysfunction, feature tracking MR strain
Background: Myocardial dysfunction is an important risk factor for failed Fontan circulation in single right ventricle (SRV) and single left ventricles (SLV).
Objective: To consider differences of myocardial function between SRV and SLV using feature tracking magnetic resonance strain.
Methods: Longitudinal, circumferential and radial strain/strain rate (SR) were measured at the basal, mid, and apical levels of the ventricle in 15 SRV and 15 SLV of similar ages (17.5±9.7 vs 17.6±10.6 years). As well, anterior to posterior wall motion delay (APWMD) was performed.
Results: Basal global circumferential strain/SR (GCS/GCSR) were lower than it at the mid (p=0.01 and 0.01) and apical (p=0.005 and 0.001) levels in SRV and SLV. There were correlation between global longitudinal (GLS/GLSR) and GCS/GCSR, and ventricular end-diastolic volume (EDV) (r=0.51 to 0.73) in SLV. However, there was only correlation between GCS/GCSR and EDV (r=0.61 and 0.7) at apical level in SRV. At all three levels, there were correlation between GCS/GCSR and ventricular end-systolic volume (ESV) (r=0.48 to 0.85) in SLV. However, there was no correlation between GCS/GCSR and ESV at basal level in SRV. APWMD was particularly found at the basal level in SRV. In SRV with large amount of atrioventricular valve regurgitation, basal GCS/GCSR were trended lower.
Conclusion: In SRV, GLS/GLSR and GCS/GCSR were not allowed to participate in ventricular size. Basal ventricular and annular dysfunction are suggested by low GCS/GCSR, APWMD and atrioventricular valve regurgitation in particular SRV.
Objective: To consider differences of myocardial function between SRV and SLV using feature tracking magnetic resonance strain.
Methods: Longitudinal, circumferential and radial strain/strain rate (SR) were measured at the basal, mid, and apical levels of the ventricle in 15 SRV and 15 SLV of similar ages (17.5±9.7 vs 17.6±10.6 years). As well, anterior to posterior wall motion delay (APWMD) was performed.
Results: Basal global circumferential strain/SR (GCS/GCSR) were lower than it at the mid (p=0.01 and 0.01) and apical (p=0.005 and 0.001) levels in SRV and SLV. There were correlation between global longitudinal (GLS/GLSR) and GCS/GCSR, and ventricular end-diastolic volume (EDV) (r=0.51 to 0.73) in SLV. However, there was only correlation between GCS/GCSR and EDV (r=0.61 and 0.7) at apical level in SRV. At all three levels, there were correlation between GCS/GCSR and ventricular end-systolic volume (ESV) (r=0.48 to 0.85) in SLV. However, there was no correlation between GCS/GCSR and ESV at basal level in SRV. APWMD was particularly found at the basal level in SRV. In SRV with large amount of atrioventricular valve regurgitation, basal GCS/GCSR were trended lower.
Conclusion: In SRV, GLS/GLSR and GCS/GCSR were not allowed to participate in ventricular size. Basal ventricular and annular dysfunction are suggested by low GCS/GCSR, APWMD and atrioventricular valve regurgitation in particular SRV.