Nobuaki Tanaka ¹, Hiroaki Yamaguchi ^1,2, Nariyasu Mano ^1,2 (1.Graduate School of Pharmaceutical Sciences, Tohoku University, 2.Department of Pharmaceutical Sciences, Tohoku University Hospital)

Takumi Tomono ¹, Kentaro Yano ², Takuo Ogihara ¹ (1.Laboratory of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Takasaki University of Health and Welfare, 2.Laboratory of biopharmaceutics, Faculty of Pharmacy, Takasaki University of Health and Welfare)

Masahiro Yahata ¹, Koji Chiba ², Yuichi Sugiyama ³ (1.Preclinical Research Laboratories, Sumitomo Dainippon Pharma Co., Ltd., Japan, 2.Laboratory of Clinical Pharmacology, Yokohama College of Pharmacy, Japan, 3.Sugiyama Laboratory, RIKEN, Japan)

Masanori Tachikawa ¹, Daichi Sano ¹, Shota Sasaki ², Makoto Kanzaki ³, Tetsuya Terasaki ¹, Toshiro Kaneko ² (1.Graduate School of Pharmaceutical Sciences, Tohoku University, 2.Graduate School of Engineering, Tohoku University, 3.Graduate School of Biomedical Engineering, Tohoku University)

Takahiro Yamashiro ¹, Tomoya Yasujima ¹, Kinya Ohta ², Katsuhisa Inoue ³, Hiroaki Yuasa ¹ (1.Graduate School of Pharmaceutical Sciences, Nagoya City University, 2.School of Pharmacy, Kinjo Gakuin University, 3.School of Pharmacy, Tokyo University of Pharmacy and Life Sciences)