Session information

Symposium

[SY-05] Symposium5
Factors that modulate the life cycle and function of drug-metabolizing enzymes: gene regulation, protein degradation, polymorphism, disease and drug toxicity

Thu. Oct 13, 2016 2:20 PM - 4:50 PM Room 1 (Great hall)

Miki Nakajima (Faculty of Pharmaceutical Sciences, Kanazawa University), Yuji Ishii (Laboratory of Molecular Life Sciences, Graduate School of Pharmaceutical Sciences, Kyushu University), Seigo Sanoh (Graduate School of Biomedical and Health Sciences, Hiroshima University)

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[SY-05-01] Role of nuclear receptors in enzyme induction and hepatocyte hypertrophy

Kouichi Yoshinari (School of Pharmaceutical Sciences, University of Shizuoka)

[SY-05-02] Molecular mechanisms of non-alcoholic fatty liver formation: Analysis using liver-specific PPARγ knockout mice

Kimihiko Matsusue (Fukuoka University)

[SY-05-03] Functional characterization of genetic variant proteins of drug-metabolizing enzymes

Masahiro Hiratsuka (Graduate School of Pharmaceutical Sciences, Tohoku University)

[SY-05-04] A-to-I RNA editing modulating drug response

Miki Nakajima (Kanazawa University)

[SY-05-05] Induction of enzyme activity owing to the accumulation of CYP3A via polyubiquitination dysfunction by acetaminophen - Possibility of novel drug-drug interactions -

Seigo Sanoh ¹, Masataka Santoh ¹, Masashi Takagi ¹, Yoko Ejiri ², Yaichiiro Kotake ¹, Shigeru Ohta ¹ (1.Graduate School of Biomedical and Health Sciences, Hiroshima University, 2.Kuraray Co., Ltd.)

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