[BP1] Finalists

[P-2] Generation of humanized CYP3A rat using mouse artificial chromosome and genome editing for prediction of xenobiotic metabolism in humans

Yasuhiro Kazuki ^1,2, Kaoru Kobayashi ³, Masumi Hirabayashi ⁴, Jiro Kuze ^1,5, Tetsushi Sakuma ⁶, Satoshi Abe ¹, Mari Hashimoto ³, Yasuko Tsukazaki ⁷, Naoto Senda ^1,7, Naoyo Kajitani ¹, Shoko Takehara ¹, Kanako Kazuki ¹, Takashi Yamamoto ^1,6, Kan Chiba ³, Mitsuo Oshimura ¹ (1.Chromosome Engineering Research Center, Tottori University, 2.Department of Biomedical Science, Institute of Regenerative Medicine and Biofunction, Graduate School of Medical Sciences, Tottori University, 3.Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University, 4.National Institute for Physiological Sciences, Center for Genetic Analysis of Behavior, 5.Taiho Pharmaceutical Co., Ltd., 6.Department of Mathematical and Life Sciences, Graduate School of Science, Hiroshima University, 7.Tsukuba Bioanalytical Laboratory, Shin Nippon Biomedical Laboratories, Ltd.)