Prediction of inter-individual differences in pharmacokinetics and drug interactions of pravastatin using physiologically based pharmacokinetics model with Monte Carlo simulation

Takeshi Matsumoto

Presentation information

Oral Presentation

[O1] 1．Transporter 1

Thu. Oct 13, 2016 9:00 AM - 10:12 AM Room 5 (The first meeting room)

Seiji Miyauchi (Toho University, Faculty of Pharmaceutical Sciences, Department of Pharmacokinetics), Takeshi Hirota (Department of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Kyushu University), Takuo Ogihara (Laboratory of Clinical Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Takasaki University of Health and Welfare), Takuya Fujita (Department of Molecular Pharmacokinetics, College of Pharmaceutical Sciences, Ritsumeikan University), )

[O1-2] Prediction of inter-individual differences in pharmacokinetics and drug interactions of pravastatin using physiologically based pharmacokinetics model with Monte Carlo simulation

Takeshi Matsumoto ¹, Kota Toshimoto ², Koji Chiba ³, Yuichi Sugiyama ² (1.Pharmaceutical Division, FUJIFILM Corporation, 2.Sugiyama Lab., RIKEN Innovation Center RIKEN, 3.Laboratory of Clinical Pharmacology, Yokohama University of Pharmacy)

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