Analysis of mechanism-based inhibition of cytochrome P450 3A4 by a series of in-house fluoroquinolone antibacterial agents

Akiko Watanabe

Presentation information

Oral Presentation

[O6] 6．Drug interaction・Toxicity

Sat. Oct 15, 2016 9:00 AM - 10:12 AM Room 5 (The first meeting room)

Kiyomi Ito (Research Institute of Pharmaceutical Sciences, Musashino University), Akihiro Hisaka (Clinical Pharmacology and Pharmacometrics, Graduate School of Pharmaceutical Sciences, Chiba University), Yasuhiro Masubuchi (Chiba Institute of Science), Ryoichi Fujiwara (School of Pharmacy, Kitasato University), )

[O6-4] Analysis of mechanism-based inhibition of cytochrome P450 3A4 by a series of in-house fluoroquinolone antibacterial agents

Akiko Watanabe ¹, Hideo Takakusa ¹, Takako Kimura ², Shin-ichi Inoue ¹, Hiroyuki Kusuhara ³, Osamu Ando ¹ (1.Drug Metabolism and Pharmacokinetics Research Laboratories, Daiichi Sankyo Co., Ltd., 2.Structural Biology Group, Biological Research Department, Daiichi Sankyo RD Novare Co., Ltd., 3.Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Science, The University of Tokyo)

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