[P2] Poster Presentation

[P-76] Modeling of CYP3A4 induction using double humanized mice of PXR/SXR and CYP3As generated by chromosome engineering technology

Daisuke Satoh ¹, Satoru Iwado ², Jiro Kuze ^1,3, Kaoru Kobayashi ⁴, Mitsuhiko Osaki ^1,2, Shoko Takehara ¹, Igarashi Katsuhide ⁵, Satoshi Kitajima ⁶, Jun Kanno ^6,7, Kan Chiba ⁴, Mitsuo Oshimura ¹, Yasuhiro Kazuki ^1,2 (1.Chromosome Engineering Research Center, 2.Graduate School of Medical Sciences, Tottori University, 3.Taiho Pharmaceutical Co., Ltd, 4.Graduate School of Pharmaceutical Sciences, Chiba University, 5.Hoshi University, 6.National Institute of Health Sciences, 7.Japan Organization of Occupational Health and Safety)