[SY-05] Symposium5
Factors that modulate the life cycle and function of drug-metabolizing enzymes: gene regulation, protein degradation, polymorphism, disease and drug toxicity

[SY-05-05] Induction of enzyme activity owing to the accumulation of CYP3A via polyubiquitination dysfunction by acetaminophen - Possibility of novel drug-drug interactions -

Seigo Sanoh ¹, Masataka Santoh ¹, Masashi Takagi ¹, Yoko Ejiri ², Yaichiiro Kotake ¹, Shigeru Ohta ¹ (1.Graduate School of Biomedical and Health Sciences, Hiroshima University, 2.Kuraray Co., Ltd.)