31th JSSX Annual Meeting in Matsumoto The Japanese Society for the Study of Xenobiotics

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Symposium

[SY-16] Symposium16
Humanized animal models for drug metabolism studies: current state and issues

Sat. Oct 15, 2016 1:20 PM - 3:50 PM Room 1 (Great hall)

Miki Nakajima (Faculty of Pharmaceutical Sciences, Kanazawa University), Kaoru Kobayashi (Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University), Yoichi Naritomi (Analysis & Pharmacokinetics Research Labs., Astellas Pharma Inc.)

[SY-16-01] CYP3A-humanized mouse model generated by chromosome engineering technology to predict pharmacokinetics and toxicity in humans

Kaoru Kobayashi 1, Yasuhiro Kazuki 2,3 (1.Laboratory of Pharmacology and Toxicology, Graduate School of Pharmaceutical Sciences, Chiba University, 2.Graduate School of Medical Sciences, 3.Chromosome Engineering Research Center, Tottori University)

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