土壌汚染対策の新展開ー新規規制・自然由来物質への対応ー

[1202] Sewage recycling of heavy metal polluted water with the use of genetically modified cyanobacteria

^○森田勇人¹, Shelake Rahul Mahadev², 林秀則² (1.愛媛大学農学部, 2.愛媛大学無細胞生命工学研究センター)

司会:駒井武(東北大学)

Keywords:藻類, 重金属, 水処理

Metal-responsive transcriptional regulations are the key features in heavy metal ion tolerance for prokaryotes.In freshwater cyanobacterium /Synechococcus/ sp. PCC 7942, /smt/ locus consists of two
divergently transcribed genes, /smtA/.( metallothionein) and /smtB/ (repressor of /smtA/transcription).
The molecular mechanism of transcription regulation and metal ion sensing with SmtB and the protein engineering techniques to improve the Zn^2+ binding ability in SmtA are studied with physicochemical techniques. We will show the results and applications of these studies.