[4O05m1] Neurodegenerative Disorders 2

[4O05m1-03] Disruption of mitochondria-associated membrane inactivates TANK-binding kinase 1, leading to impairment of stress granule formation and motor dysfunction

*Seiji Watanabe¹, Kotaro Oiwa^1,2, Koji Yamanaka¹ (1. RIEM, Nagoya Univ, Aichi, Japan, 2. Grad Sch Med, Nagoya Univ, Aichi, Japan)

Keywords:mitochondria-associated membranes, TANK-binding kinase 1 (TBK1), Sigma 1 receptor, amyotrophic lateral sclerosis (ALS)