[Pe-071] English Poster Session 071「Neurogenetics, Gene therapy, and iPS cell 4」

[Pe-071-4] siRNA-mediated ATN1 mRNA knockdown markedly improves the phenotype of DRPLA model mice

Mitsuto Sato^1,2, Mitsunori Yamada², Shin Shimada³, Takahiro Yoshizawa³, Toshiya Sato⁴, Cantley William⁵, Shoji Tsuji^6,7, Yoshiki Sekijima^1,8 (1.Department of Medicine (Neurology and Rheumatology), Shinshu University School of Medicine, Japan, 2.Department of Brain Disease Research, Shinshu University School of Medicine, Japan, 3.Research Center for Advanced Science and Technology, Shinshu University, Japan, 4.Department of Laboratory Animal Science, Kitasato University School of Medicine, Japan, 5.Alnylam Pharmaceuticals, USA, 6.Department of Neurology, Graduate School of Medicine, The University of Tokyo, Japan, 7.Institute of Medical Genomics, International University of Health and Welfare, Japan, 8.Institute for Biomedical Sciences, Shinshu University, Japan)