[1P] Alzheimer's Disease and Dementia

Wed. Jul 29, 2020 1:30 PM - 3:30 PM Poster Session

*Videos are available throughout the meeting period.

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[1P-206] Development of an EEG-based baiomarker for cognitive assessment

Industry-Academia Collaboration Presentation

*Ryohei P Hasegawa, Ryohei P. Hasegawa, Yoshiko Nakamura, Mayuko Takehara (AIST, Tsukuba, Japan)

[1P-207] Exploring the roles of TIAM2S in Alzheimer's disease

*Li-Yun Wang, Ya-Hsin Hsiao (Department of Pharmacology, College of Medicine, National Cheng-Kung University, Tainan, Taiwan)

[1P-208] Effect of SUMO modification on synaptic function and Alzheimer disease pathology

*Hironori Takamura^1,2, Shinsuke Matsuzaki^2,3, Taiichi Katayama², Ottavio Arancio⁴, Paul E. Fraser^1,5 (1.Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto, Toronto, Canada, 2.United Graduate School of Child Development, Osaka University, Osaka, Japan, 3.Department of Pharmacology, Wakayama Medical University, Wakayama, Japan, 4.Department of Pathology and Cell Biology and Taub Institute for Research on Alzheimer's Disease and the Aging Brain, Columbia University, New York, USA, 5.Department of Medical Biophysics, University of Toronto. Toronto, Canada)

[1P-209] The role of progranulin in neurite outgrowth involved in acidification of lysosomes

*Yoshinori Tanaka, Kosuke Takeya, Masumi Eto (Biochem Unit, Dept of Vet Med, Okayama Univ of Science, Ehime, Japan)

[1P-210] Non-spatiotemporal-encoding hyperactivity is elevated in the hippocampal CA1 region of Alzheimer's disease model mice

*Risa Takamura^1,2,3,4, Kotaro Mizuta^1,4, Yukiko Sekine^3,4, Tanvir Islam^3,4, Takashi Saito^3,4,5, Masamichi Ohkura^6,7, Junichi Nakai^6,8, Toshio Ohshima², Takaomi C Saido^3,4, Yasunori Hayashi^1,4,6 (1.Dept. Med, Univ of Kyoto, Kyoto, Japan, 2.Dept. Life Sci and Med Biosci, Waseda Univ, Tokyo, Japan, 3.BSI, RIKEN, Saitama, Japan, 4.CBS, RIKEN, Saitama, Japan, 5.Dept. Neurocognitive Sci, Nagoya City Univ, Nagoya, Japan, 6.BBSSI, Saitama Univ, Saitama, Japan, 7.Dept. Pharmacol, Kyushu Univ of Health and Welfare, Miyazaki, Japan, 8.Grad Sch Dentistry, Tohoku Univ, Miyagi, Japan)

[1P-211] Autophagy regulates extracellular release of Aβ via exosome secretion

*Shingo Koinuma^1,3, Nobuhiro Shimozawa², Yasuhiro Yasutomi², Takeshi Nakamura³, Nobuyuki Kimura¹ (1.Dept. of Alzheimer's Disease, Research Inst., National Center for Geriatrics and Gerontology (NCGG), 2.National Inst of Biomed Innov, Health and Nut, Ibaraki, Japan, 3.RIBS, Tokyo Univ of Science, Tokyo)

[1P-212] Reduced density of noradrenergic fibers without prominent neuron loss or tau pathology in the locus coeruleus in App knock-in mouse models of Aβ amyloidosis

*Yasufumi Sakakibara¹, Kyoko Ibaraki¹, Kimi Takei¹, Takashi Saito², Takaomi C Saido³, Michiko Sekiya^1,4, Koichi M Iijima^1,4 (1.Dept. of Alzheimer's Disease Research, National Center for Geriatrics and Gerontology, Aichi, Japan, 2.Dept. of Neurocognitive Sci., Nagoya City Univ. Grad. Sch. Med. Sci., Aichi, Japan, 3.Lab. for Proteolytic Neurosci., RIKEN CBS, Saitama, Japan, 4.Dept. of Experimental Gerontology, Nagoya City Univ. Grad. Sch. Pharm. Sci., Aichi, Japan)

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